CV Elena Lazzeri

CURRICULUM VITAE ET STUDIORUM

  • Medicine and Surgery Degree acquired in 1987/88 years at Medicine and Surgery Faculty of University of Study of Pisa.
  • Nuclear Medicine bachelor acquired in July 1994 at the University of Study of Pisa.
  • External Universitary Professor in School of Specialization of Nuclear Medicine from 2004 to 2015 at University of Studies of  Pisa
  • Responsible of Diagnosis of Infectious Diseases at Regional Center of Nuclear Medicine of A.O.U.P. Pisa from 2004.
  • Director of Simple Structure of Nuclear Medicine, Cardio-Thoracic Department, A.O.U.P. Pisa from 2004.

UNIVERSITY ACTIVITY

  • Attended, as guest researcher, Research laboratory on fibrinolysis and coagulation of National Institute of Dental Research at National Institute of Health in Bethesda (Washington) under supervision of Dr. S.I. Chung (July-August 1987).
  • Attended, as internal and specialization student, Nuclear Medicine Institute of the University of Studi of Pisa under supervision of Prof. Romano Bianchi (1988 al 1993).
  • Attended, as teacher, to course of students of 3rd year of School of Specialization of Nuclear Medicine of the University of Studies of Pisa (1995-1998).
  • Attended, as teacher, to cells and peptides labeling courses organized by Prof. Signore at University of Study of Sapienza of Rome in years 1997, 1999, 2001, 2006, 2010 and 2013.
  • Attended, as Professor with formal contract with the Univesity of Study of Pisa, to 3rd year of School of Specialization in Nuclear Medicine from 2004 to 2015
  • Attended, as teacher, to course for radiology technicians organized by Grosseto Hospital (February 2002).
  • Attended, as teacher, Nuclear Medicine Course for nuclear medicine physicians organized by Clinic Physiology Institute of CNR e AIMN (September 2003).
  • Attended, as speaker,, to Consensus Conference on “Guide-lines in the diagnosis of osteo-articular infections” in Ferrara (March 2004).
  • Attended, as teacher, to Tuscany Regional Course AIDS 2005-2006 for infettivologists in 2006 and 2013.
  • PhD University of Groningen (The Netherland) in Groningen (May 2009).
  • AIMN National Coordinator of working study group “Infection-Inflammation” from 2010 to 2015.
  • 2010-2013. Member of EANM Committee of “Inflammation and Infection”.
  • 2013-2017. Vice-chair of EANM Committee of “Inflammation and Infection”.
  • 2014-2016 Member of EANM Committee of “Congress Strategy”
  • Reviewer of procedural Guidelines of Italian Association of Nuclear Medicine “Infection-inflammation” and “Labelling of blood elements” 2011
  • 2014-present Expert Consultant for education/training in developing countries organized by the Nuclear Medicine Section of the IAEA (Vienna, Austria).
  • 2015-2016 Teacher of the European School of Nuclear Medicine (ESNM) for Theoretical and Practical Courses on Infection and Inflammation
  • 2016-present Certified Speaker of European School of Multimodality Imaging and Therapy (ESMIT)
  • 2017-present Senior Advisor of EANM Committee of “Inflammation and Infection”.

PAPERS IN INTERNATIONAL JOURNALS

Bernini G.P., Gasperi M., Mariotti F., Miccoli P., Molea N., Lazzeri E., Goletti O., Franchi F. Endocrine-scintigraphic evaluation of 13 patients with asymptomatic adrenal masses. Journal of Endocrinological Investigation, vol. 14, suppl. 2 to 4, 1991.

Nicolini A, Ferrari P, Boni G, Colombini C, Lazzeri E, Ferla R, Matteucci F, Metelli MR, Ferdeghini M, Anselmi L. Tumor markers, bone scanning and radiological examinations for the differential diagnosis of bone metastases in breast cancer. J Nucl Med Biol, 1994; 38(3): 481-82.

Mariani G, Molea N, La Civita L, Porciello G, Lazzeri E, Ferri C, Scintigraphic findings on 99mTc-MDP, 99mTc-sestamibi and 99mTc-HMPAO images in Gaucher’s disease. Eur J Nucl Med 1996; 23: 466-470.

La Civita L, Mariani G, Porciello G, Viacava P, Molea N, Lazzeri E., Pasero G, Ferri C. Bone involvement in Gaucher’s disease: “bone crisis” or disease complication? Clin Exper Rheumatol 1996; 14: 195-198.

Di Bello V, Bellina CR, Gori E, Molea N, Talarico L, Boni G, Magagnini E, , Matteucci F, Giorgi D, Lazzeri E, Bertini A, , Bianchi R, Giusti C. Incremental diagnostic value of dobutamine stress echocardiography and dobutamine scintigraphy (99m Tc MIBI-SPECT) for assessment of presence and extent of coronary artery disease. Journal of Nuclear Cardiology. Vol 3, N° 3, 212-220. May-June1996

Mazzeo S, Caramella D, Lencioni R, Molea N, De Liperi A, Marcocci C, Miccoli P, Iacconi P, Bruno Bossio G, Viacava P, Lazzeri E, Bartolozzi C. Comparison among sonography, double-tracer subtraction scintigraphy and double-phase scintigraphy in the detection of parathyroid lesions. AJR:166, June 1996.

Di Bello V, Bellina CR, Molea N, Talarico L, Boni G, Magagnini E, , Matteucci F, Giorgi D, Lazzeri E, Bertini A,Romano MF , Bianchi R, Giusti C. Simultaneous dobutamine stress echocardiography and dobutamine scintigraphy (99mTc-MIBI-SPET) for assessment of coronary artery disease, International journal of cardiac imaging, num 3, vol 12, p. 185, 1996

Cavina E, Goletti O, Molea N, Buccianti P, Chiarugi M, Boni G,  Lazzeri E, Bianchi R Trocar site tumor recurrences. May pneumoperitoneum be responsible? Surgical endoscopy-ultrasound and interventional techniques, num. 11, vol 12, p 1294, 1998

Lazzeri E., Manca M., Molea N., Marchetti S., Consoli V., Bodei L., Bianchi R., Chinol M., Paganelli G., Mariani G. Clinical validation of the avidin/indium-111 biotin approach for imaging ingection/inflammation in orthopaedic patients. Eur J Nucl Med 1999, 26:606-614.

G. Carulli, E. Lazzeri, G. Lagomarsini Scintigraphic imaging with 99mTc-HMPAO labelled leukocytes in neutropenia due to increased neutrophil sequestration. Haematologica 2000; 85:1214.

Lazzeri E, Pauwels EK, Erba PA, Volterrani D, Manca M, Bodei L, Trippi D, Bottoni A, Cristofani R, Consoli V, Palestro CJ, Mariani G. Clinical feasibility of two-step streptavidin/111In-biotin scintigraphy in patients with suspected vertebral osteomyelitis. Eur J Nucl Med Mol Imaging. 2004 Nov;31(11):1505-11. Epub 2004 Jul 06.

Prandini N., Lazzeri E., Rossi B., Erba P., Parisella M.G., SignoreA. Nuclear medicine imaging of bone infections Nucl Med Comm 2006. 27:633-644.

Concia E., Prandini N., Massari L., Ghisellini F., Consoli V., Menichetti F., Lazzeri E.  Osteomyelitis: clinical update for practical guidelines Nucl Med Comm 2006. 27:645-660.

G. Carulli, E. Lazzeri, G. Lagomarsini, A. Zucca, E. Canizzo, R. Riccioni, M. Petrini. Recombinant human granulocyte colony-stimulating factor administration in a case of neutropenia due to increased neutrophil sequestration. Clin Ter 2007. 158(3):235-237.

Dardano A, Ballardin M, Ferdeghini M, Lazzeri E, Traino C, Caraccio N, Mariani G, Barale R, Monzani F. Anticlastogenic effect of ginkgo biloba extract in graves’ disease patients receiving radioiodine therapy. J Clin Endocrinol Metab. 2007 Nov;92(11):4286-9.  

Lazzeri E., Erba P, Perri M, Tascini C,  Doria R,  Giorgetti J,  Mariani G. Scintigraphic Imaging of Vertebral Osteomyelitis with 111In-Biotin. Spine. 2008 Apr 1;33(7):198-204. 

Perri M, Erba P, Volterrani D, Lazzeri E, Boni G, Grosso M, Mariani G. Octreo-SPECT/CT imaging for accurate detection and localization of suspected neuroendocrine tumors. Q J Nucl Med Mol Imaging. 2008 May

A Signore, C. D’Alessandria, E. Lazzeri, R. Dierckx. Can we produce an image of bacteria with radiopharmaceuticals? Eur J Nucl Med Mol Imaging 2008 June;35(6):1051-5

Perri M, Erba P, Volterrani D, Lazzeri E, Boni G, Grosso M, Mariani G.  Octreo-SPECT/CT imaging for accurate detection and localization of suspected neuroendocrine tumors. Q J Nucl Med Mol Imaging. 2008 Dec;52(4):323-33.

Lazzeri E., Erba P., Perri M, Doria R, Tascini C, Mariani G.  Clinical Impact of SPECT/CT with 111In-Biotin on the Management of Patients with Suspected Spine Infection Clin Nucl Med. 2010 Jan;35(1):12-7

Erba PA, Manfredi C, Lazzeri E, Minichilli F, Pauwels EK, Sbrana A, Strauss HW, Mariani G. Time course of Paclitaxel-induced apoptosis in an experimental model of virus-induced breast cancer. J Nucl Med. 2010 May;51(5):775-81.

Erba P, Cataldi G., Tascini C. Leonildi A., Mariani G., Lazzeri E. 111In-DTPA-Biotin uptake by Staphylococcus aureus Nucl Med Commun 2010 Nov;31(11):994-7

Perri M, Erba P, Volterrani D, Guidoccio F, Lazzeri E, Caramella D, Mariani G. Adrenal masses in patients with cancer: PET/CT characterization with combined CT histogram and standardized uptake value PET analysis. AJR Am J Roentgenol. 2011; 197:209-16.

Erba PA, Conti U, Lazzeri E, Sollini M, Doria R, De Tommasi SM, Bandera F, Tascini C, Menichetti F, Dierckx RA, Signore A, Mariani G. Added value of 99mTc-HMPAO-labeled leukocyte SPECT/CT in the characterization and management of patients with infectious endocarditis. J Nucl Med. 2012 Aug;53(8):1235-43

Signore A, Glaudemans AW, Malviya G, Lazzeri E, Prandini N, Viglietti AL, De Vries EF, Dierckx RA. Development and testing of a new disposable sterile device for labelling white blood cells. Q J Nucl Med Mol Imaging. 2012 Aug;56(4):400-8

Erba PA, Sollini M, Lazzeri E, Mariani G. FDG-PET in cardiac infections. Semin Nucl Med. 2013 Sep;43(5):377-95

P. Jutte, E. Lazzeri, N. Petrosillo, A. Signore Diagnostic flowcharts in osteomyelitis, spondylodiscitis and prosthetic joint infection. Q J Nucl Med Mol Imaging. 2014 Mar;58(1):2-19.

B. Iung, P. Erba, N. Petrosillo, E. Lazzeri Common diagnostic flowcharts in infective endocarditis Q J Nucl Med Mol Imaging. 2014;58:55-65

Lazzeri E, Israel O, Erba PA, Chakravartty R, Comin JM, Jamar F, Rouzet F, Glaudemans AW, Signore A  Comment on Aksoy et al.: FDG and FDG-labelled leucocyte PET/CT in the imaging of prosthetic joint infection. Eur J Nucl Med Mol Imaging. 2014 May;

Sollini M., Boni R., Traino A. C., Lazzeri E., Pasqualetti F., Modeo L., Mariani G., Petrini M., Erba P. A. New approaches for imaging and therapy of solid cancer Q J Nucl Med Mol Imaging 2015;59:168-83

Glaudemans AW,  Jutte P., Petrosillo N., Erba P., Lazzeri E., Signore A. Comment on Diaz-Ledezma C. et al: Diagnosis of Periprosthetic Joint Infection: The role of Nuclear Medicine may be overestimated J of Arthroplasty 2015;

Lazzeri E. Systematic Review of in vivo microorganisms imaging with labeled vitamins, bacteriophages and oligomers Clin Transl Imag 2016;4:265-272

Sollini M, Pasqualetti F, Perri M, Coraggio G, Castellucci P, Roncali M, Boni R, Lazzeri E, Galeandro M, Paiar F, Versari A, Erba PA   Detection of a second malignancy in prostate cancer patients by using [18F]Choline PET/CT: a case series Cancer Imaging. 2016 Aug 31;16(1):27

Fuente A, Zanca R, Boni R, Cataldi AG, Sollini M, Lazzeri E, Mariani G, Erba PA. Miniaturized Radiochemical Purity Testing for 99mTc-HMPAO, 99mTc-HMDP, and 99mTc-Tetrofosmin. J Nucl Med Technol. 2017 Sep;45(3):236-240.

Ebenhan T, Lazzeri E, Gheysens O. Imaging bacteria: is there any hope for the future based on past experience? Curr Pharm Des 2018;24:1-16


Glaudemans AW, Prandini N, Di Girolamo M, Argento, Lauri C, Lazzeri E, Muto M, Scofienza LM, Signore A Hybrid imaging of musculoskeletal infections QJNMMI 2018 March;62(1):3-13

Sollini M, Lauri C, Boni R, Lazzeri E, Erba PA, Signore A. Current status of molecular imaging in infections Curr Pharm Des. 2018;24:

Signore A,  Jamar F,  Israel O,  Buscombe J, Martin-Comin J, Lazzeri E Clinical indications, image acquisition and data interpretation for white blood cells and anti-granulocyte monoclonal antibody scintigraphy  Eur J Nucl Med Mol Imaging. 2018 submitted

Lazzeri E, Muto M, Bozzao A, Petrosillo N, Cataldo A, Signore A Joint EANM and ESNR (and ESCMID endorsed) Guideline for the diagnosis of Spine Infection in Adults. Spine 2018 submitted

National and International Congresses Attendance of last 5 years

  • 2013
  • Torino (Italy) March: National Congress of Italian Nuclear Medicine Association as editor of Session “Infection-Inflammation: Paediatric infections, Infections of cardiovascular system and FUO”
  • Pisa (Italy) March: Corso AIDS as speaker of “Le infezioni delle protesi ortopediche:
    la diagnosi del Medico Nucleare”
  • Modena (Italy) Ottobre: Corso aggiornamento SIMIT  as author of “La PET nell’approccio diagnostico e nel follow-up della spondilodiscite”
  • Lyon (France) October: European Congress of Nuclear Medicine Medicine as author of oral communication “Infective Endocarditis: the nuclear medicine” and as chairwoman of session:
  • Pisa (Italy) December: International Atomic Energy Association Course as speaker of oral communications “Pathophysiologic principles of radionuclide imaging of infection/inflammation” and “Hybrid imaging of osteomyelitis “
  • Rome (Italy) December: Imaging Infections and inflammation: 1st European Theoretical and Practical course SPECT/PET as organizer and speaker of the communications “SPECT/PET studies for vertebral infections” and “Techniques for in vitro labelling of WBC and devices for WBC labelling”
  • 2014
  • Bangkok (Thailand) March: IAEA Mission for teaching labelling of autologous white blood cells visit to Ministry of Science and Technology, Office of Atoms for Peace.
  • Verona (Italy) March: Course on Nuclear Medicine Imaging on infective diseases as speaker of “I quesiti dell’Ortopedico: le possibili risposte del medico nucleare” and “Diagnostica medico-nucleare delle spondilodisciti”
  • Mantova (Italy) April: Updating National Course of Italian Association of Nuclear Medicine as teacher on “Le protesi articolari, fratture e processi infiammatori-osteomieliti: Ruolo della PET”
  • Firenze (Italy) April: International Course on Diabetic Foot as speaker on “OSTEOMYELITIS: Is there a gold standard for diagnosis of osteomyelitis? the nuclear medicine specialist”
  • Negrar (VR) (Italy) May: 1st National Course of Interdisciplinar Group of Radiopharmaceuticals (GICR) as speaker of  “L’input del processo : l’infezione e l’infiammazione”
  • Castelbolognese (Italy) May: Course on Good practice in in nuclear medicine  radiopharmacy as speaker on “NBP, Mediafill e Marcature cellulari”
  • Pisa (Italy) June: Congress on La fibrosi polmonare idiopatica: un approccio multidisciplinare as speaker of “TR-IPF: l’imaging e l’inquadramento  diagnostico: Ruolo della Medicina Nucleare”
  • Goteborg (Sweden) October: European Congress of Nuclear Medicine Medicine as speaker of oral communication “Low back pain in immune-compromised patients” in CME “Low back pain”, coauthor of poster “Scintigraphy with 99mTc-HMPAO-labeled leukocytes in patients admitted to the Intensive Care Unit with fever of unknown origin (FUO) and as chairwoman of two oral sessions: PET/MRI and Cardiovascular Infection-inflammation.
  • Pisa (Italy) as teacher at Summer SchoolUp-to-date meThods for the Radiolabelling Of Peptides, Immunoconjugates and Cells, and their(pre)cinicAL appLication” – TROPI-CALL on “Radiolabelling of white blood cells (WBCs)” and “Clinical application: radiolabelled WBCs and antibodies”
  • 2015
  • Rimini (Italy) April: National Congress of Italian Nuclear Medicine Association as editor of Sessions “Scintigraphic Imaging of Acute Infection-Inflammation” and “Clinical Cases of Infection-Inflammation”
  • Wien (Austria) June:as teacher at ESNM Practical Course on Infection and Inflammation.
  • Napoli (Italy) September 38th ESNR Annual Meeting as speaker on “»Special Focus: Spondilodiscitis Update: Nuclear Medicine diagnosis»
  • Hamburg (Germany) October: European Congress of Nuclear Medicine Medicine as speaker of oral communication “Pitfalls and artefacts in Imaging Inflammation and Infection: Labelled Leucocytes and oral communication on “Overview on Inflammation/Infection and Standardized cell Labelling Procedure”
  • Wien (Austria) November: IAEA Meeting of CRF on Spondylodiscitis “Evaluation of Multimodality Imaging in the diagnosis and assessment of post-operative spinal infections”
  • 2016
  • Wien (Austria) June: as teacher at ESNM Practical Course on Infection and Inflammation.
  • Beograd (Serbia) September: as speaker of oral communication “Role of Nuclear Medicine Imaging in Musculoskeletal Infections”
  • Barcelona (Spain) September: European Congress of Nuclear Medicine Medicine as speaker of oral communication “Imaging in Painful Spine (including the new joint EANM-ESNR-ESCMID endorsed Guidelines for Imaging Spondylodiscitis)
  • Roma (Italy) December: 2nd European Congress Imaging Infections and Inflammation as organizer and speaker of the communication “Spondylodiscitis: Nuclear Medicine Imaging”
  • Roma (Italy) December: as teacher at Theoretical and Practical Course of white blood cells labelling with Leukokit
  • 2017
  • Groningen (The Netherlands) March: as teacher of Musculo-Skeletal-Track at ESMIT Spring School
  • Rimini (Italy) March: National Congress of Italian Nuclear Medicine Association as speaker of communication “Imaging di Infezioni-Infiammazioni: cosa c’è di nuovo? Scintigrafia con leucociti marcati o anticorpi monoclonali: quali vantaggi e svantaggi?”
  • Denver (Colorado, USA) June: SNM annual meeting as speaker of oral communications “Available Guidelines on Musculoskeletal Infections” and “Spondylodiscitis: Role of Imaging for Diagnosis and Monitoring Treatment Response: PET/CT”
  • Pisa (Italy) October: Summer School “TROPI-CALL” as speaker of “Basic Radiopharmaceuticals for imaging of inflammation/infection”
  • Vienna (Austria) October: European Congress of Nuclear Medicine Medicine as speaker of oral communications “Pitfalls and Artefacts in Imaging Inflammation and Infection: Labelled Leucocytes” and “68Ga-Biotin”
  • Wien (Austria) December: IAEA Meeting of CRF on Spondylodiscitis “Evaluation of Multimodality Imaging in the diagnosis and assessment of post-operative spinal infections”
  • 2018
  • Bergamo (Italy) February: as teacher ofMusculo-Skeletal-Track at ESMIT Winter School
  • BOOKS
  • Le fratture dell’arto superiore nello Sport. V convegno Ortopedia e Sport. ACSI. Febbraio 2001
  • La scintigrafia in otorinolaringoiatria. Quaderni monografici di aggiornamento. Febbraio 2003
  • Fondamenti di Medicina Nucleare.  Springer 2010
  • Medicina Nucleare: Tecniche Metodologie Applicazioni  Idelson-Gnocchi 2010
  • La qualità nella preparazione dei radiofarmaci  Springer 2011
  • Atlas of SPECT/CT Springer 2011
  • Radionuclide imaging of infection and inflammation: A Pictorial Case-based Atlas. Springer 2012
  • Diagnostic imaging of infections and inflammatory diseases: a multidisciplinary approach. J. Whiley 2013
  • Atlas de Inflamacion e infeccion en Medicina Nuclear Aula Médica 2017